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聂磊 副教授
发布时间:2022年02月27日 13:01    作者:    点击:[]



聂磊,博士,副教授,山东大学药学院药物分析研究所秘书,分析化学教研室工作。1989年至1993年聊城师范学院化学系化学教育专业,获理学学士学位,1996年至1999年中国科学技术大学分析化学专业,获理学硕士学位,1999年至2002年中国科学技术大学分析化学专业,获理学博士学位,2002年至2004年清华大学化学系药物研究所做博士后工作(助研),2007年至2008年美国康奈尔大学(Cornell University)食品科学技术系访问学者,2015年美国纽约州立大学布法罗分校(University at Buffalo)药学院访问学者。

主要从事中药质量控制及评价方法研究(包括指纹图谱构建方法及相关分析及谱效关系研究等),近红外光谱分析方法研究,蛋白质组学及代谢组学分析。

主要担任本科生必修课《分析化学》、《分析化学实验》、选修课《光谱与色谱分析原理及在医药中的应用》和研究生课程《现代仪器分析与应用》、《现代药分选论》、《现代近红外光谱分析技术的应用》和《国际药事管理与质量控制》(全英授课)的教学工作。

近期发表代表性文章:

[1] Yue Sun, Meng Yuan, Xiaoyan Liu, Mei Su, Linlin Wang, Yingzi Zeng, Hengchang Zang, Lei Nie*, A sample selection method specific to unknown test samples for calibration and validation sets based on spectra similarity, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 258: 119870.

[2] Yue Sun, Meng Yuan, Xiaoyan Liu, Mei Su, Linlin Wang, Yingzi Zeng, Hengchang Zang, Lei Nie*,Comparative analysis of rapid quality evaluation of Salvia miltiorrhiza (Danshen) with Fourier transform near-infrared spectrophotometer and micro near-infrared spectrophotometer, Microchemical Journal,2020,159:105492.

[3] Xiaoyan Liu, Hui Zhang, Mei Su, Yue Sun, Hongming Liu, Hengchang Zang*, Lei Nie*, Comprehensive quality evaluation strategy based on non-targeted, targeted and bioactive analyses for traditional Chinese medicine: Tianmeng oral liquid as a case study, Journal of Chromatography A, 2020, 1620: 460988.

[4]刘肖雁,姜文文,蒋海强,苏美,孙越,臧恒昌,曾英姿,聂磊*,基于“谱-效-代”关联的参枝苓口服液质量标志物的初步研究,中草药,2019,50(19):4603-4612.

[5] Xiaoyan Liu, Wenwen Jiang, Mei Su, Yue Sun, Hongming Liu*, Lei Nie*, Hengchang Zang, Quality evaluation of traditional Chinese medicines based on fingerprinting, Journal of separation science, 2019, 1-12, DOI: 10.1002/jssc.201900365.

[6] Wenwen Jiang, Yue Sun, Xiaoyan Liu, Mei Su, Hengchang Zang, Yingzi Zeng ,Hongming Liu*, Lei Nie*, Rapid quality evaluation of Shenzhiling oral liquid by attenuated total reflectance-infrared spectroscopy with chemometrics, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 223: 117-324.

[7] Wenwen Jiang, Xiaoyan Liu, Mei Su, Hengchang Zang, Yingzi Zeng, Lei Nie*, Chromatographic fingerprint based on serially coupled columns combined with multiple- component quantitation with a single reference standard for quality evaluation of Shen–Zhi–Ling oral liquid, Analytical Methods, 2019,11: 367-374.

[8] Jie Zhou, Lei Nie (co-first authors), Bin Zhang, Guizheng Zou*, Spectrum-Resolved Triplex-Color Electrochemiluminescence Multiplexing Immunoassay with Highly-Passivated Nanocrystals as Tags, Analytical Chemistry, 2018, 90 : 12361-12365.

[9] Zhongyu Sun , Jiayue Wang, Lei Nie*, Lian Li, Dawei Cao, Jiajin Fan, Haiyan Wang, Ruichen Liu, Yinran Zhang, Hengchang Zang*, Calibration transfer of near infrared spectrometers for the assessment of plasma ethanol precipitation process, Chemometrics and Intelligent Laboratory Systems, 2018,181: 64-71.

[10] Xiaomeng Shen, Shichen Shen, Jun Li, Qiang Hu, Lei Nie, Chengjian Tu, Xue Wang, David J. Poulsen, Benjamin C. Orsburn, Jianmin Wang, and Jun Qu*,IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts, PNAS, May 9, 2018. 201800541. https://doi.org/10.1073/ pnas.1800541115.


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